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Pierre Giraud est ingénieur d’études à l’Université de La Réunion depuis 2011. Il a obtenu son master recherche en 2006 à l’Université Pierre et Marie Curie (Paris VI) et son doctorat en 2010 en biochimie structurale au CNRS (Centre National de la Recherche Scientifique) à Gif sur Yvette. Depuis 2011 le Dr Giraud apporte son expertise dans le domaine de la production et purification des protéines recombinantes, de la gestion du laboratoire et de la maintenance des appareils du laboratoire.
EXPERIENCE 2011 - Présent : Ingénieur d'études - Université de La Réunion 2010-2011 : Ingénieur de recherche - Université de La Réunion EDUCATION 2001-2010 Pierre and Marie Curie University doctorat, biochimie structurale |
Technics and methods:
- Microbiologie : culture bactérienne, ensemencement, induction, surexpression de protéines d’intérêt
- Biochimie : électrophorèse agarose, SDS PAGE, chromatographie sur système AKTA pure 25, ultracentrifugation, microfluidique
- Caractérisation : Résonance Magnétique Nucléaire (RMN), Spectrométrie de masse
- Logistique : maintenance appareils, gestion des stocks, inventaire
- Administratif : gestion des devis, commandes, réception
- Hygiène et sécurité : sauveteur secouriste du travail, assistant de prévention
Publications
Production, characterization and biodistribution of therapeutic high-density lipoprotein-like nanoparticles reconstituted with or without histidine-tagged recombinant ApoA1.
Rosanaly S, Apalama ML, Bringart M, Giraud P, Allard B, Veeren B, Meilhac O, Couprie J, Rondeau P. Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Apr;1870(3):159606. doi: 10.1016/j.bbalip.2025.159606. PMID: 39986649.
Aerosolized ApoA1 Nanoparticles Synthesized by Microfluidics Cross the Lung Barrier and Modulate Inflammation.
Apalama ML, Givran L, Navarette B, Bringart M, Giraud P, Rondeau P, Meilhac O, Allard B. bioRxiv. 2025. doi: 10.1101/2025.07.09.663869.
Production and characterization of Apolipoprotein A1 nanoparticles as a new therapeutic vector for lung diseases.
Apalama ML, Givran L, Navarette B, Giraud P, Bringart M, Rondeau P, Meilhac O, Allard B. ERS Congress 2025 Abstracts. 2025. doi: 10.1183/13993003.congress-2025.PA4594.
Curcumin-Encapsulated Nanomicelles Promote Tissue Regeneration in Zebrafish Eleutheroembryo.
Narra SS, Gence L, Youssouf L, Couprie J, Giraud P, Diotel N, Lefebvre D'Hellencourt C. Zebrafish. 2023 Oct;20(5):200-209. doi: 10.1089/zeb.2023.0007. PMID: 37643300.
Development, synthesis, and 68Ga-Labeling of a Lipophilic complexing agent for atherosclerosis PET imaging.
Yong-Sang J, Dioury F, Meneyrol V, Ait-Arsa I, Idoumbin JP, Guibbal F, Patché J, Gimié F, Khantalin I, Couprie J, Giraud P, Benard S, Ferroud C, Jestin E, Meilhac O. Eur J Med Chem. 2019 Aug 15;176:129-134. doi: 10.1016/j.ejmech.2019.05.002. PMID: 31102933.
Enhanced effects of curcumin encapsulated in polycaprolactone-grafted oligocarrageenan nanomicelles, a novel nanoparticle drug delivery system.
Youssouf L, Bhaw-Luximon A, Diotel N, Catan A, Giraud P, Gimié F, Koshel D, Casale S, Bénard S, Meneyrol V, Lallemand L, Meilhac O, Lefebvre D'Hellencourt C, Jhurry D, Couprie J. Carbohydr Polym. 2019 Aug 1;217:35-45. doi: 10.1016/j.carbpol.2019.04.014. PMID: 31079683.
Glycation of human serum albumin impairs binding to the glucagon-like peptide-1 analogue liraglutide.
Gajahi Soudahome A, Catan A, Giraud P, Assouan Kouao S, Guerin-Dubourg A, Debussche X, Le Moullec N, Bourdon E, Bravo SB, Paradela-Dobarro B, Álvarez E, Meilhac O, Rondeau P, Couprie J. J Biol Chem. 2018 Mar 30;293(13):4778-4791. doi: 10.1074/jbc.M117.815274. PMID: 29414771. Free PMC article.
Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human.
Nativel B, Couret D, Giraud P, Meilhac O, Lefebvre d'Hellencourt C, Viranaïcken W, Robert Da Silva C. Sci Rep. 2017 Nov 17;7(1):15789. doi: 10.1038/s41598-017-16190-y. PMID: 29150625. Free PMC article.
Ultrasound-assisted extraction and structural characterization by NMR of alginates and carrageenans from seaweeds.
Youssouf L, Lallemand L, Giraud P, Soulé F, Bhaw-Luximon A, Meilhac O, Lefèbvre D'Hellencourt C, Jhurry D, Couprie J. Carbohydr Polym. 2017 Jun 15;166:55-63. doi: 10.1016/j.carbpol.2017.01.041. PMID: 28385248.
Oxidative damage in diabetics: insights from a graduate study in La Reunion University.
Girard D, Rondeau P, Catan A, Planesse C, Giraud P, Bourdon E. Biochem Mol Biol Educ. 2014 Sep-Oct;42(5):435-442. doi: 10.1002/bmb.20818. PMID: 25132514.
Rosanaly S, Apalama ML, Bringart M, Giraud P, Allard B, Veeren B, Meilhac O, Couprie J, Rondeau P. Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Apr;1870(3):159606. doi: 10.1016/j.bbalip.2025.159606. PMID: 39986649.
Aerosolized ApoA1 Nanoparticles Synthesized by Microfluidics Cross the Lung Barrier and Modulate Inflammation.
Apalama ML, Givran L, Navarette B, Bringart M, Giraud P, Rondeau P, Meilhac O, Allard B. bioRxiv. 2025. doi: 10.1101/2025.07.09.663869.
Production and characterization of Apolipoprotein A1 nanoparticles as a new therapeutic vector for lung diseases.
Apalama ML, Givran L, Navarette B, Giraud P, Bringart M, Rondeau P, Meilhac O, Allard B. ERS Congress 2025 Abstracts. 2025. doi: 10.1183/13993003.congress-2025.PA4594.
Curcumin-Encapsulated Nanomicelles Promote Tissue Regeneration in Zebrafish Eleutheroembryo.
Narra SS, Gence L, Youssouf L, Couprie J, Giraud P, Diotel N, Lefebvre D'Hellencourt C. Zebrafish. 2023 Oct;20(5):200-209. doi: 10.1089/zeb.2023.0007. PMID: 37643300.
Development, synthesis, and 68Ga-Labeling of a Lipophilic complexing agent for atherosclerosis PET imaging.
Yong-Sang J, Dioury F, Meneyrol V, Ait-Arsa I, Idoumbin JP, Guibbal F, Patché J, Gimié F, Khantalin I, Couprie J, Giraud P, Benard S, Ferroud C, Jestin E, Meilhac O. Eur J Med Chem. 2019 Aug 15;176:129-134. doi: 10.1016/j.ejmech.2019.05.002. PMID: 31102933.
Enhanced effects of curcumin encapsulated in polycaprolactone-grafted oligocarrageenan nanomicelles, a novel nanoparticle drug delivery system.
Youssouf L, Bhaw-Luximon A, Diotel N, Catan A, Giraud P, Gimié F, Koshel D, Casale S, Bénard S, Meneyrol V, Lallemand L, Meilhac O, Lefebvre D'Hellencourt C, Jhurry D, Couprie J. Carbohydr Polym. 2019 Aug 1;217:35-45. doi: 10.1016/j.carbpol.2019.04.014. PMID: 31079683.
Glycation of human serum albumin impairs binding to the glucagon-like peptide-1 analogue liraglutide.
Gajahi Soudahome A, Catan A, Giraud P, Assouan Kouao S, Guerin-Dubourg A, Debussche X, Le Moullec N, Bourdon E, Bravo SB, Paradela-Dobarro B, Álvarez E, Meilhac O, Rondeau P, Couprie J. J Biol Chem. 2018 Mar 30;293(13):4778-4791. doi: 10.1074/jbc.M117.815274. PMID: 29414771. Free PMC article.
Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human.
Nativel B, Couret D, Giraud P, Meilhac O, Lefebvre d'Hellencourt C, Viranaïcken W, Robert Da Silva C. Sci Rep. 2017 Nov 17;7(1):15789. doi: 10.1038/s41598-017-16190-y. PMID: 29150625. Free PMC article.
Ultrasound-assisted extraction and structural characterization by NMR of alginates and carrageenans from seaweeds.
Youssouf L, Lallemand L, Giraud P, Soulé F, Bhaw-Luximon A, Meilhac O, Lefèbvre D'Hellencourt C, Jhurry D, Couprie J. Carbohydr Polym. 2017 Jun 15;166:55-63. doi: 10.1016/j.carbpol.2017.01.041. PMID: 28385248.
Oxidative damage in diabetics: insights from a graduate study in La Reunion University.
Girard D, Rondeau P, Catan A, Planesse C, Giraud P, Bourdon E. Biochem Mol Biol Educ. 2014 Sep-Oct;42(5):435-442. doi: 10.1002/bmb.20818. PMID: 25132514.